Formulation and Evaluation of Buspirone Hydrochloride Buccal Films by Vandana...
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Item specifics
- Condition
- ISBN
- 9783844315851
- Subject Area
- Technology & Engineering, Science, Psychology, Medical
- Publication Name
- Formulation and Evaluation of Buspirone Hydrochloride Buccal Films
- Publisher
- LAP Gmbh & Company KG
- Item Length
- 9 in
- Subject
- Textiles & Polymers, Materials Science / General, Spectroscopy & Spectrum Analysis, Psychopathology / Anxieties & Phobias, Pharmacology, Chemistry / General
- Publication Year
- 2011
- Type
- Textbook
- Format
- Trade Paperback
- Language
- English
- Item Height
- 0.3 in
- Item Weight
- 8 Oz
- Item Width
- 6 in
- Number of Pages
- 148 Pages
About this product
Product Identifiers
Publisher
LAP Gmbh & Company KG
ISBN-10
3844315853
ISBN-13
9783844315851
eBay Product ID (ePID)
122828119
Product Key Features
Number of Pages
148 Pages
Language
English
Publication Name
Formulation and Evaluation of Buspirone Hydrochloride Buccal Films
Subject
Textiles & Polymers, Materials Science / General, Spectroscopy & Spectrum Analysis, Psychopathology / Anxieties & Phobias, Pharmacology, Chemistry / General
Publication Year
2011
Type
Textbook
Subject Area
Technology & Engineering, Science, Psychology, Medical
Format
Trade Paperback
Dimensions
Item Height
0.3 in
Item Weight
8 Oz
Item Length
9 in
Item Width
6 in
Additional Product Features
Synopsis
Buspirone Hydrochloride is used in the treatment of anxiety. It has a short half life and low oral bioavailability of 5%. Therefore, the purpose of this research was to develop unidirectional Bucco- adhesive films of Buspirone Hydrochloride by solvent casting technique using full factorial designs. HPMC K15M and Eudragit RL-100 were used as polymers in different proportion. Polyethylene glycol 400 was used as plasticizer and Sodium lauryl sulphate was used as permeation enhancer in different concentration. The physicochemical compatibility of the drug and the polymers was studied by FT-IR spectroscopy. The results suggested no physicochemical incompatibility between the drug and the polymers. In full factorial designs, total amount of polymer (X1) and percentage of HPMC K15M (X2) was kept as a independent variables. After wards, statistically optimization process was carried out and two optimized formulation (OF1 and OF2) was developed. The results of optimization formulation showed greater degree of % similarity with predicted values. Stability studies of two optimized formulations were carried out at room temperature as per ICH Q1C guidelines.
Item description from the seller
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- b***r (528)- Feedback left by buyer.Past 6 monthsVerified purchaseItem was as described.. new, still sealed at a decent price.. great communication, packaging and shipping.. not one issue, thank youMario & Luigi: Brothership - Nintendo Switch (#167279801681)
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Seller feedback (2,826)
- b***r (528)- Feedback left by buyer.Past 6 monthsVerified purchaseItem was as described.. new, still sealed at a decent price.. great communication, packaging and shipping.. not one issue, thank youMario & Luigi: Brothership - Nintendo Switch (#167279801681)
- e***e (194)- Feedback left by buyer.Past 6 monthsVerified purchaseAwesome seller. Great communication. Item came brand new and sealed just as described. Thank you and God bless.Far Cry Primal - Sony PlayStation 4 (#166889064750)
- l***o (2170)- Feedback left by buyer.Past 6 monthsVerified purchaseGood communications, fast shipping, well packed, item as described, A+ sellerNFPA 101, Life Safety Code : 2024 Edition by National Fire Protection... (#167317044538)