I have been very impressed with the results of Devil's Claw for my arthritic knee pain. I have gone from taking Aleve 2+ times per day, plus acetaminophen and Ibuprofen on top of that for constant pain in one knee, to taking nothing else daily. I have taken 2 Aleve total since I received & began taking Devil's Claw 1-2 weeks ago and it seems to even last more than a day. I am still testing this out for this specific issue with my knee, but so far I believe this is the reason my knee has stopped hurting all the time like it had been doing for the past 2 years or so. This stuff is also pretty inexpensive and hopefully does not harm my liver or kidneys like OTC NSAID's do, but I honestly do not know and wish I knew more.